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The multifaceted mechanism of action of 5FU involves direct incorporation of its metabolites into DNA (FdUTP) and RNA (FUTP), as well as inhibition of thymidylate synthase (TS) via FdUMP 4,5 , making it more difficult to identify rational combination partners that would enhance clinical responses without eliciting adverse systemic toxicity

As Medical Director at Silk Clinics in Dubai Healthcare City, I see patients every week who arrive looking for "a skin glow drip" and leave understanding something much more interesting: that what they were really feeling was their antioxidant reserves running thin

Rev Infect Dis 7:341356 Michael E, Bundy DAP (1997) Global mapping of lymphatic filariasis