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Future research is also needed to explore the antidepressant effects of LAC acting as part of a system network with other important mediators of brain plasticity in comparison with classical antidepressant drugs with particular focus on the effects in specific phenotypes of depression well-characterized not only for the individual endogenous levels of LAC but also for the corresponding changes in metabolic and inflammatory pathways as well as for history of adverse childhood experiences
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The increase was almost 36% between 2023 and 2024
This pharmacovigilance system allows patients, carers, and healthcare professionals to report any suspected side effects from medicines, vaccines, and medical devices including those that are unlicensed or used off-label
Arch.Pharm Res 2012;35(11):1945-1952
It is patented worldwide by BIOSINT SpA (58.5% l-carnitine, 41.5% fumaric acid, US patent number 4,602,039)
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