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Elevated substance P content in sputum and plasma in patients with COPD and its relationship with FEV1/FVC

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IGF-1 LR3's resistance to IGF binding proteins gives it a half-life measured in hours, which makes it suitable for study designs that need sustained systemic exposure or repeated-measures protocols where researchers want signaling active across a full observation day

Not all smokers develop COPD, but of those that do, the vast majority are over 60 years old [19]

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