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In a recent study, Liskiewicz and colleagues discovered that long-acting GIP receptor agonists activate GABAergic neurons that express the GIP receptor in the area postrema, and that GIP receptor signaling in GABAergic neurons is necessary for the effects of GIP to lower body weight [151]

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The rectal suppository is a solid dosage form that is inserted into the rectum, where it dissolves or melts at body temperature

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