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The FDA decision is expected in mid-2026

LDL-C is a well-established causal factor in ASCVD, while elevated triglyceride (TG)-rich lipoproteins and lipoprotein(a) [Lp(a)] have also been strongly linked to increased cardiovascular risk

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Compared to the CD signal of 2.5 mM l-carnitine, the CD signal of the supernatant in l-carnitine-AuNR tube reduced by half, which suggested that the concentration of l-carnitine in the supernatant decreased significantly

Brefeldin A (BFA), a ER-to-Golgi transport inhibitor, and monensin, a Golgi-to-PM transport inhibitor, abrogated VRK2 overexpression induced increase in the expression of SLC7A11 at PM level (Fig