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These medications mimic the hormone GLP-1 (glucagon-like peptide-1), which is naturally released after eating
If someone is on semaglutide and we switch them to tirzepatide, often, theyre going to experience more weight loss. But she notes that the response can vary from person to person
Key takeaways Tirzepatide usually starts at a low weekly dose, then increases in small steps no sooner than every 4 weeks, based on response and tolerability
10.1016/j.ctrv.2006.09.006 57 SharmaH.MishraP
Week 4 and beyond: Maintenance For those whose symptoms have resolved or significantly improved, you can gradually resume dose escalation if you had stepped down
It does not slot neatly into an endocrine signaling cascade
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