first shot of semaglutide what to expect Shot: Side Effects & not feeling anything on semaglutide

Petersenn S, Rasch AC, Heyens M, Schulte HM

GLP-1 receptor agonists and breast cancer: metabolic insights and clinical implications

is contracted via the University of Groningen (no personal payment) to undertake consultancy for Novo Nordisk, Eli Lilly and Boehringer Ingelheim

Diabetologia 56 , 22662274 (2013)

Mechanisms of Action: From Obesity to Addiction GLP-1 agonists enhance insulin secretion, slow gastric emptying, and promote satiety by acting on GLP-1 receptors in the hypothalamus and other brain regions involved in hunger regulation

They: Increase insulin secretion in response to meals Suppress glucagon, a hormone that raises blood sugar Slow gastric emptying, which helps you feel full longer Reduce appetite, often leading to weight loss This combination makes them effective for both diabetes management and weight reduction Nausea is a common side effect when starting GLP-1 medications because they slow digestion and affect appetite signals in the brain