Heres what they do: Help your body release insulin when your blood sugar is high Reduce another hormone called glucagon that usually increases blood sugar Slow down digestion , so you feel full for longer Send signals to your brain to curb hunger and reduce cravings This multi-action approach is what makes GLP-1 drugs helpful in both type 2 diabetes and weight management If Our Body Already Makes GLP-1, Why Take It From Outside
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It is also found in blood vessels, the intestinal lining, and other organs, where it is essential for flexibility, strength, and healing
According to clinical trial data reported by reputable sources like the Mayo Clinic and Cleveland Clinic, tirzepatide generally leads to more significant weight loss than semaglutide
Understanding how these medications work throughout the body is important when considering potential side effects, as GLP-1 receptors are present in multiple organ systems beyond the pancreas, including the gastrointestinal tract, cardiovascular system, and central nervous system
NICE guidance supports their use as part of NHS services for selected patients