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Not that it's been disproven

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The relative changes in the penile erectile function between l-ARG and placebo subgroups of patients with severe vasculogenic ED are shown in Table 4

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Gale GR et al

62 In this context, our results support a model in which Trim37 -deficient PGCs exit the germline program and enter an aberrant somatic-like state marked by partial and heterogeneous activation of multiple somatic gene programs, rather than bona fide lineage-restricted transdifferentiation