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Paul Joyce emphasized that the findings come from animal research and should be interpreted with caution

After 2 to 3 missed weeks, blood levels drop enough that restarting at your previous dose can cause the same GI side effects you experienced during initial titration

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It tends to happen the most in people who are going off-script with compounded semaglutide and taking much more than even the highest dose recommended by Ozempic or in people who are combining medications like Ozempic with other medications like Tirzepatide or other appetite-suppressing medications