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The medium used to maintain the pellet was full chondrogenic medium (CM) consisted of DMEM (Gibco), 2 anti-anti (Gibco), 10 g/ml ITS (Thermo Fisher Scientific), 0.1 M Dexamethasone (Sigma-Aldrich, St

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10.1038/s41467-025-61901-z 19

Early metabolic changes may be reflected in lab work before they are visible in the mirror

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