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Regulatory challenges, including the approval process for new drug formulations, also pose a hurdle for market players aiming to innovate and expand their product lines
GLP-1 drugs slow gastric emptying and may alter lipid handling, requiring baseline assessment
Most surgical guidelines recommend stopping semaglutide injections 2 to 4 weeks before elective surgery to allow gastric function to return to baseline
PLoS One 16:e0247060
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Furthermore, as for cardiac fibroblasts, GLP-1RAs inhibit Ang II and glucose-induced collagen formation via decreasing phospho-NF-B-p65 and phospho-ERK1/2 expression [169] (Figure 2)
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