First and foremost, it demonstrates that FDA-approved drugs can be repurposed for treating cancer, specifically overcoming chemotherapy resistance, saving valuable time and money
Phytoconstituents like flavonoids and alkaloids demonstrate broad pharmacological effects, including antioxidant, anti-inflammatory, and anticancer activities
conducted a study revealing that curcumin-loaded liposomal nanoemulsions exhibited superior percutaneous absorption and sustained release compared to plain liposomes or curcumin solution, hence confirming the synergistic effect of liposomes and nanoemulsions in transdermal applications [304]
It would also be pertinent to add laboratory assays that allow putting the results in the larger context of cellular senescence, which seems to be disturbed in several disorders where fatigue has been associated with mitochondrial dysfunction
10.1111/j.1600-0560.2009.01256.x 63 SugiharaH.YonemitsuN.MiyabaraS.YunK
62 Fatty fish (like salmon, mackerel, and sardines), walnuts, and flaxseeds are rich in omega-3 fatty acids that may help protect and sustain glutathione levels by reducing oxidative stress