An injection delivers it directly, avoiding the need for absorbtion from the stomach (see Pernicious anaemia) no guesswork, no barriers
To avoid possible side effects, it should therefore not be taken
The benzyl alcohol preservative can accumulate in infants, causing severe toxicity
We have ZERO data on this risk because there are NO long-term human studies
This presents problems to my patients that have either candida hypersensitivity or Gluten sensitivity
Saland J, Leavey PJ, Bash RO, Hansch E, Arbus GS, Quigley R (2002) Effective removal of methotrexate by high-flux hemodialysis