1998;139(5):552-561 Giustina A, Veldhuis JD
Significantly, a major challenge currently lies in the selective targeting of lactylation without affecting other PTMs, as they are intricately linked and share a common set of regulatory enzymes, such as p300, HDACs, and Sirts, complicating the specific inhibition of lactylation
This is not a set it and forget it type of treatment
10.1007/s00394-024-03546-0 378 RaviM.MillerA
Just like stopping insulin or blood-pressure tablets, weight can return if you dont have a long-term plan- healthy food, strength training, and sometimes maintenance doses or lifestyle support
As hormone balance is restored and patients experience more restorative sleep and have more energy, they often find it easier to partake in additional healthy lifestyle habits like regular exercise