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Why it matters: NAD+ levels naturally decline with age, stress, illness, poor sleep, and intense physical or mental demand

Experimental Neurology 2004

Telomerase, an enzyme complex containing both protein and RNA components, can add nucleotide sequences back to telomeres, potentially extending cellular lifespan

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Products may contain impurities, synthesis byproducts, or fillers that can lead to allergic reactions or toxicity, she says

doi: 10.1056/NEJMoa2032183 9 WhartonSFreitasPHjelmesthJKabischMKandlerKLingvayIet al