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Methods Trial Design, Subjects, and Dosing This was a clinical pharmacology, single-center, parallel-group, randomized, double-blind, placebo-controlled trial with two doses of semaglutide (0.5 mg and 1.0 mg) administered subcutaneously to healthy male Caucasian and Japanese subjects

All other reagents, unless otherwise indicated, were purchased from Sigma-Aldrich (St Louis, MO, USA)

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