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Originally developed as an anti-obesity drug candidate in the late 1990s, it has since found research applications in both metabolic studies and cartilage repair investigations

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It is classified as a triple incretin receptor agonist, meaning it simultaneously targets three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

Clinical data from metabolic syndrome models show MOTS-c administration improves insulin sensitivity by 3040% and reduces visceral adiposity without caloric restriction

Stier H., Vos E., Kenley D

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