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D.GrassiS.WilliamsC.Kaiser-KupferS.MarainiM.HejtmancikG.J

Statistics and reproducibility For animal experiments, the sample size was 6 independent mice per group

Results showed dose-dependent weight loss: the 0.25mg dose produced 4.5% additional weight loss beyond diet and placebo, the 0.5mg dose achieved 9.2% weight loss, and the 1.0mg dose resulted in 10.6% weight lossrepresenting approximately twice the efficacy of other approved obesity drugs available at that time