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(PubMed) Ledezma E, DeSousa L, Jorquera A, et al

Kidney Issues: Semaglutide usage has, in rare cases, been linked to kidney problems, which can be exacerbated by dehydration

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Functionally, cagrilintide activates amylin receptors AMY1R, AMY2R, AMY3R and the calcitonin receptor (CTR), binding via a conserved bypass motif involving mid-segment residues (S19 P25) (Cao et al