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severe gastrointestinal disease (including gastroparesis)
Mice lacking endothelial nitric oxide synthase ( eNOS / mice) display normal radiolabel appearance into plasma as wild-type controls, however, GLP-2 treatment in these mice did not increase plasma 3 H compared to treatment in wild-type mice (Hsieh et al., 2015)
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reduction in liver fat content liver fat accumulation is correlated with several metabolic disturbances including low HDL and elevated triglyceride levels(Tushuizen et al, 2006)
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A dipeptidyl peptidase-4 inhibitor, sitagliptin, exerts anti-inflammatory effects in type 2 diabetic patients
While it shares the weight loss indication with some GLP-1 medications, the mechanism and side effect profile are entirely different
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