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Intervention of brain-derived neurotrophic factor and other neurotrophins in adult neurogenesis

Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats

With regard to the increased secretion of EVs during the progression of NAFLD, experimental studies demonstrated that toxic lipids significantly increase the production of hepatocyte-derived EVs, which act as mediators of paracrine signaling, causing hepatic stellate cell activation, angiogenesis and activation of macrophages leading to inflammation and chemotaxis [103,104,105]