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The dose is escalated gradually from 0.25 mg to 0.5 mg, then to 1 mg, and where clinically necessary, to 2 mg always under the guidance of a healthcare professional
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And then, when you move all the way up to tirzepatide, which is the first and only dual agonist, it's actually a GLP-1 receptor agonist, GIP agonist, you're now talking about 15 to 25% body weight loss, which- Advertisement John Horton: that's a lot
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Genetics, gut microbiome composition, baseline GI health, concurrent medications, and individual amylin receptor sensitivity all contribute to this variation
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