doi:10.1186/s40168-020-00875-0 23
Pharmacokinetic parameters such as AUC, maximum plasma concentration (Cmax), terminal elimination t1/2, volume of distribution (Va), and clearance were calculated [2]
Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture
VRK2 expression stratifies the response of PC to GSH-targeted treatment To further investigate the differential sensitivity to GSH inhibitors between VRK2-expressing and VRK2-deficient pancreatic tumors in vivo, we developed orthotopic pancreatic cancer models using Pan02 cells (Fig
For example, in a mouse model of lipopolysaccharide-induced neuro-inflammation and Alzheimers disease, FMN supplementation with specific nanoparticles targeting riboflavin metabolism in the microglia ameliorated cognitive dysfunction, synaptic plasticity, and inflammation 71
A glutathione precursor that supports respiratory health and liver function