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Four studies altered meal patterns, such as having a heavy breakfast or dinner, consuming carbohydrates at dinner, and varying meal frequency (e.g., 3 or 6 meals per day)

GLP-1 Receptor Glucagon-like peptide-1 receptor, a protein found in pancreas, brain, stomach, and other tissues

Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones

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JAMA, 332 (7), 571584

The science makes sense when you break it all down