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In order to test this possibility, we engineered a murinized version of the anti-IGF-1R mAb, L2-C (L2-Cmu), in order to reduce effector function and enable chronic administration in mice
Poor reconstitution technique can degrade the peptide, introduce contamination, or create an inconsistent solution where some draws are more concentrated than others
A lot of early tests were conducted on rats, mice, chickens, and other animals, revealing potential benefits across different organs [3]
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