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And our current thinking about obesity, and one of the components of the disease of obesity, is that some individuals although they all have GLP-1 and these other gut hormones, amylin, glucagon, GIP, that's what they're called that signal, for some reason, is not getting to the brain in ample amounts to tell the individual to feel full, satiated, and stop eating

Figure 36

A study from ScienceDirect shows that medications working as dual agonists might need slow dose increases so patients start experiencing less hunger

It helps me to stay healthy, and I have a lot of energy

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In other words, the medication may be quieting the very signals that set off a migraine in the first place