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Description

The only molecules that can passively diffuse across the BBB are gases such as oxygen and carbon dioxide, and small lipid-soluble molecules with a molecular weight under 400 Da or containing less than 8 hydrogen bonds (e.g., ethanol, antidepressants) [17]

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[PMID: 33153401] * Neag, M

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doi: 10.1167/iovs.06-0889

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