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In trigeminal neuralgia models, curcumin ameliorates chronic pain-induced depression by modulating lipid and glycerophospholipid metabolism-potentially key pathways in pain-depression comorbidity (Zhang L

(Side note: it took a bit longer to realize that the brain was more than cushion stuffing for the head it was routinely thrown out when bodies of pharaohs were preserved for mummification)

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Common approaches include 4 weeks on followed by 2 weeks off, 6 weeks on followed by 4 weeks off, or running continuously until the injury resolves and then stopping