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So far, several unimolecular dual and triple agonists are in clinical evaluation and as of today, the improved metabolic efficacy does not seem to be compromised by reduced safety [25].
Ipamorelin mimics ghrelin and stimulates GH release with no significant increase in ACTH or cortisol (Raun et al., European Journal of Endocrinology )
doi: 10.3389/fnut.2023.1294057 37
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But they are not interchangeable, and the right choice depends on how each medication works, your medical history, and how your body responds during treatment
Potential applications of GH secretagogs in the evaluation and treatment of the age-related decline in growth hormone secretion
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