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In RE rats, activation of the NF-B pathway was found to result in the release of large amounts of TNF- and IL-6 (63)
et al., Altern Ther Health Med (2021) Small case series on BPC-157 for knee pain (author-affiliated clinic) Lee E
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Emergence of autoreactive IgG3 may cause the acute onset of the disease [162], which on account of the potent immune-activating properties of IgG3 points to immune activation being a pathological driver
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