The KIT gene controls mast cell creation from stem cells in the bone marrow, and mutations in KIT cause excess mast cell proliferation.[ref][ref] A mastocytosis diagnosis is either systemic mastocytosis (affecting the whole body) or cutaneous mastocytosis, which has more skin-related symptoms
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BMJ 324:15125, PMID: 12077044 Passeri M, Cucinotta D, Abate G, Senin U, Ventura A, Stramba BM, Diana R, La Greca P, Le Grazie C (1993) Oral 5-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study
Ray, Thiocyanate in excess develops goiter followed by auto immune thyroid diseases even after effective salt iodization in a rural community of north east India
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