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doi:10.1056/NEJMoa2307563 Jastreboff AM, Kaplan LM, Frias JP, et al

PubMed laboratory research record [PMID: 40991302] PubMed record related to this compound for laboratory literature review

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Efinopegdutide has been granted fast track designation by the FDA for the treatment of MASH (NCT04944992, NCT05877547) and this is the indication that the clinical development programme of this molecule will focus

while significant pharmacokinetic interactions with psychiatric medications are not generally expected, GLP-1 agonists may affect absorption of some oral medications due to delayed gastric emptying Discuss realistic expectations regarding weight loss and diabetes control to avoid disappointment that might affect mood Ensure adequate support systems are in place, including regular contact with healthcare providers Discuss pregnancy plans as these medications are not recommended during pregnancy or breastfeeding