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doi: 10.1016/j.jcjd.2019.05.005 38 ChoiJGWinnANSkandariMRFrancoMIStaabEMAlexanderJet al

Researchers should note that some immortalized cell lines (particularly HEK293) express relatively low IGF-1R and may require receptor overexpression constructs to achieve meaningful signaling responses

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