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The broader class includes liraglutide and dulaglutide as GLP-1 receptor agonists and tirzepatide as a GIP/GLP-1 dual agonist, the latter studied in SURMOUNT (NEJM, 2022) and SURMOUNT-OSA (NEJM, 2024)

With the growing understanding of MASLD and ongoing research, it is anticipated that the integration of artificial intelligence and non-invasive biomarkers will enhance the development of diagnostic criteria for MASLD in the future (102, 103)

Some users report difficulty sleeping on injection night, though this is less common than the nausea benefit is helpful

Overall dietary compliance, based on the excitotoxin FFQ, was excellent throughout the 6-week period (including 4-week intervention period and the 2-week challenge period) (69)

Track range of motion using simple home tests (how far can you reach, bend, rotate)

For semaglutide to work best, its important to know how to properly give yourself an injection