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Even though there are studies showing an effective and safe reduction of glycaemic parameters with initial combination therapies with DPP-4 inhibitors, initial combinations are not generally recommended in the new treatment recommendations (7072, 7685)
Bai, C., Zhong, Q
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Exendin-based Glucagon-like Peptide-1 Receptor Agonists and Anaphylactic Reactions: a Pharmacovigilance Analysis
Supplemental doses usually range from 0.5 to 2 g/day (133)
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