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Tregs secrete immunosuppressive factors like IL-10 and transforming growth factor beta 1 (TGF-1), contributing to decreasing inflammation, supporting tissue repair, and preserving immune tolerance [143]

Twelve-month-old female Sprague-Dawley aged OVX rats have been observed to increase the mRNA level of OPG while decreasing RANKL mRNA after 16 weeks of exendin-4 use ( Conclusion and Expectations Many scientific investigations have focused on the impact and mechanisms of therapies based on insulin-stimulating hormones, such as GLP-1

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