This mechanistic diversity enables applications across a broad spectrum of medical conditions and continues to expand as new targets and approaches are identified
The integration of deep generative models and molecular dynamics simulations has further accelerated antifungal discovery
However, under a chronic glucolipotoxic environment, persistent hyperglycemia disrupts mitochondrial and endoplasmic reticulum homeostasis to trigger extensive oxidative stress and advanced glycation end-product accumulation, which directly activates various intracellular signaling cascades to initiate RCD pathways (14) ( Table 1 )
No head-to-head trial has compared them, so better cannot be answered directly
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