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But if the patient brought in their own medication then all things would change
The conformational changes in IGF-IR create docking sites for its substrates, such as Shc and InsR substrates (IRS), which relay the signaling to downstream effectors including PI3K, MAPK, and STAT3
Koh, I.-O., & Thiemann, W.H.-P
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Sharma A, Kaur P, Kumar V, Gill KD
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