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Villa E, Ali ES, Sahu U, Ben-Sahra I

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Castelletto V et al

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Risk-benefit assessment : For patients with multiple cardiovascular risk factors or established cardiovascular disease, tirzepatide's demonstrated benefits for glycemic control, weight reduction, and improvement in cardiovascular risk factors should be weighed against theoretical long-term risks

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Initially, the agonist properties of these ligands were compared to GLP-1 in a cAMP-sensitive luciferase reporter gene assay (CRE-luc) and revealed potency as reported previously (Fig

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Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes

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