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Providers could leverage this window to optimize patient evaluations, address unmet diagnostic needs, and establish comprehensive care plans

Pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate

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Without this, efficacy plummets, and harms skyrocket

This vessel normalization window is characterized by a rescue of the balance between pro- and anti-angiogenic factors and it can promote increase tumor drug delivery and efficacy