tirzepatide off fda shortage list is NO longer in SHORTAGE. What You Need to Know Dr. Marc Siegel: These weight

Dosage and Administration: Determining optimal dosages and administration routes for a combined regimen is complex and would require expert guidance

Because of its weight-loss effects, it may sometimes be prescribed off-label to support weight management in people with or without diabetes

You may also have costs associated with managing side effects or additional monitoring, as directed by your provider

Source: FDA briefing document, July 2026

Cost Analysis Cost can significantly impact the choice between Trulicity and Mounjaro, as patients often consider their out-of-pocket expenses alongside the benefits provided by each medication

Figure 2: Diabetes and Incretin effect