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One reason for the contradictory results of RGD-GHK binding in vitro and in vivo could be that high-molecular-weight peptide hindered the penetration and retention of sOtx2-GHK in the skin

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The route of administration was noted to affect quality of life as was frequency of dosing, although the magnitude of impact in the economic evaluation was considered large based on clinical expert opinion

(2012) The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial

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