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Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]

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Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA): A targeted antioxidant strategy to counter oxidative stress in retinopathy

H.ShawR

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Br J Dermatol