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Missing data on key clinical factors (such as body mass index and type 2 diabetes duration) may contribute to residual confounding, leaving uncertainty about whether the observed association is causal

This mix-up could lead to patients taking the wrong medication, posing risks such as ineffective treatment, drug interactions, or potential side effects

The inclusion criteria were as follows: the study type must be an RCT

The combination creates serious risks including hypoglycaemia, dehydration, nutritional deficiencies, and worsening gastrointestinal side effects, as Mounjaro already significantly reduces appetite and food intake

Muscle preservation: Most weight lost was body fat rather than lean tissue, though some muscle loss is expected with any significant weight reduction