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Dosing and Administration The oral Wegovy requires daily dosing on an empty stomach with a small amount of water
Which form has fewer side effects
GLP-1 RAs are available in both injectable and oral forms
The drug is not FDA-approved for weight loss
Who Should Not Switch Patients with active or recent pancreatitis, personal or family history of medullary thyroid carcinoma (MTC), or multiple endocrine neoplasia type 2 (MEN2) should not be initiated on any GLP-1 receptor agonist, including retatrutide [4]
Additionally, PPAR activation inhibits transcription factors like NF- B, preventing atherosclerosis by suppressing the expression of cytokines and adhesion molecules in endothelial cells
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