doi: 10.1302/2046-3758.33.2000226 94 PanFWangYLimYZUrquhartDMEsteeMMWlukaAEet al
Budiman ME, Bubenik JL, Miniard AC et al (2009) Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporation
3 To prevent excessive oxidative stress and maintain favorable redox homeostasis, tumor cells have evolved a complex antioxidant defense system that strategically adjusts multiple antioxidant enzymes such as catalase, glutathione reductase, and antioxidant molecules
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Reduced glutathione levels improved in erythrocytes, plasma, lymphocytes and buccal cells in only 1 month
However, a local drastic lowering or prolonged depression of glutathione under pathogenic conditions could gradually induce neuronal damage