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In conclusion, the use of melatonin as an adjunctive therapy for sepsis treatment significantly reduced inflammatory biomarkers and improved clinical conditions in neonates, but larger scale studies with higher validity are needed to demonstrate clear clinical benefits of the therapy 103,105,107,108,109

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Look at factors like meal timing, portion sizes, protein intake, physical activity, and medication adherence

The apparent volume of distribution at steady state is large relative to body water volume, indicating substantial distribution into peripheral tissues

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