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PPP metabolizes 5-30% of glucose, depending on tissue type
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The most parsimonious hypothesis is simply that this is a case of a viral protease targeting a cellular gene for cleavage, for which there are abundant precedents, including the proposed M pro targeting of TRMT1 and HDAC2 (9), and HIV-1 protease, which can be toxic to cells, via its action at various cellular targets (15)
ACS Appl Mater interfaces
Supplements aren't held to the same standards by the FDA as medications, which means you can't always know exactly what's in your supplement or in what amounts
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