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Cancer Metastasis Rev 2013
Summary GLP-1 receptor agonists have four main characteristics: strong hypoglycemic effect, weight loss, lower incidence of hypoglycemia than other hypoglycemic agents, and more cardiovascular benefits
19, 73 It is not known whether those muscular abnormalities are usually primary pain generators (giving rise to associated secondary bladder pain) or are themselves secondary phenomena elicited by the primary bladder pain of IC/BPS
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25 Given concerns that skeletal muscle loss may predispose patients to long-term metabolic complications, including sarcopenia, it is recommended that individuals undergoing treatment with GLP-1 RAs receive adequate protein intake and appropriate micronutrient supplementation to preserve muscle mass and function, thereby maximizing the clinical benefits of therapy
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